Artrite Reumatoide e Dieta

Uno studio svedese condotto in un gruppo di più di 30000 donne ha dimostrato che la  regolare assunzione di acidi grassi Omega-3 si associa ad un 35% di probabilità in meno di contrarre l’artrite reumatoide (AR) nel breve termine. Il rischio di contrarre l'AR si riduce di oltre il 50% in caso di consumo prolungato di Omega-3.

L'articolo, dunque, indica  un ruolo potenzialmente importante degli Omega-3 nell’eziologia dell’artrite reumatoide e suggerisce che il consumo regolare e protratto di pesci grassi quali salmone e sgombro (ricchi di Omega-3)  può  generare benefici rispetto al rischio di artrite reumatoide.

Di seguito riportiamo l'abstract dell'articolo proposto. 

Buona lettura 
Laboratorio di analisi e poliambulatorio Polo Biomedico Adriatico


 2013 Aug 12. doi: 10.1136/annrheumdis-2013-203338. [Epub ahead of print]

Long-term intake of dietary long-chain n-3 polyunsaturated fatty acids and risk of rheumatoid arthritis: a prospective cohort study of women.

Source

Division of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

Abstract

OBJECTIVES:

To analyse the association between dietary long-chain n-3 polyunsaturated fatty acids (PUFAs) and incidence of rheumatoid arthritis (RA) in middle-aged and older women from the Swedish Mammography Cohort, a population-based prospective study.

METHODS:

Data on diet were collected in 1987 and 1997 via a self-administered food-frequency questionnaire (FFQ). The risk of RA associated with dietary long-chain n-3 PUFAs and fish intake was estimated using Cox proportional hazard regression models, adjusted for age, cigarette smoking, alcohol intake, use of aspirin and energy intake.

RESULTS:

Among 32 232 women born 1914-1948, 205 RA cases were identified during a mean follow-up of 7.5 years (1 January 2003 to 31 December 2010; 2 41 120 person-years). An intake of dietary long-chain n-3 PUFAs (FFQ1997) of more than 0.21 g/day (lowest quintile) was associated with a 35% decreased risk of developing RA (multivariable adjusted relative risk (RR) 0.65; 95% CI 0.48 to 0.90) compared with a lower intake. Long-term intake consistently higher than 0.21 g/day (according to both FFQ1987 and FFQ1997) was associated with a 52% (95% CI 29% to 67%) decreased risk. Consistent long-term consumption (FFQ1987 and FFQ1997) of fish ≥1 serving per week compared with

CONCLUSIONS:

This prospective study of women supports the hypothesis that dietary intake of long-chain n-3 PUFAs may play a role in aetiology of RA.

 

 


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